Eat and drink more than you think you should, once you get behind there is no catching up.
It's super important to always be taking in calories and to aim for at least 300 calories per hour (I tend to push it to 400-450/hr) but it all depends on what your body is able to handle. Once you get behind, there's not really any "catching up" as your body can only digest at a certain rate, but your constantly burning through your energy stores at a faster rate.
2. Focus on things you can control: like your nutrition plan.
3. Never Panic when $h&T happens. Most situations can be solved if you stay calm.
First is in regard to my body. I want to make sure that my nutrition and hydration is dialed in and my stomach is able to absorb as many calories as possible. It's really hard to eat solid foods on these rides so this year I've been focusing on consuming 80% my calories via liquid. This is through high calorie sports drinks, gels, and liquid shots. The goal is not to "bonk".
The second is my choice in tires. I DO NOT want to flat or really have any mechanical issues during the race. My choice of tire this year is the Continental Terra Speed 45c tire with a ton of sealant in there. If I do get a puncture I will have easily accessible plugs and a CO2 to quickly fix the leak.
2. FUELING & HYDRATION. Bring a variety of food. Eat early and often. But, after 10-12+ hours on the bike, flavor fatigue is inevitable. Some sort of savory or salty snack later in the race is crucial. And so is hydrating properly, early and often, with appropriate amounts of electrolytes. Drink before you get thirsty and eat before you get hungry!